Getting medicines to those who need them most
We recognize that the patients and families who battle serious, life-threatening diseases anxiously await more effective medicines with each passing day. Knowing this drives us to work harder to deliver transformative treatments more swiftly.
We also seek to ensure any medicine we develop is safe and effective and follows the rigorous guidelines established by regulatory agencies.
We strive to balance these two complementary and vital goals in all that we do.
Our clinical trials
Systemic mastocytosis (SM)
A clinical trial for people with indolent systemic mastocytosis
Trial Phase
Target Population
Indolent SM
Study Status
Active, fully enrolled
ClinicalTrials.gov
Study Number
NCT03731260
A clinical trial for people with advanced systemic mastocytosis
Trial Phase
Target Population
Aggressive SM, SM with associated hematologic neoplasm and mast cell leukemia
Study Status
Active, fully enrolled
ClinicalTrials.gov
Study Number
NCT03580655
A clinical trial for people with indolent systemic mastocytosis
Trial Phase
Target Population
Indolent SM
Study Status
Active, recruiting
ClinicalTrials.gov
Study Number
NCT04910685
Learn more: clinicaltrials.gov/ct2/show/NCT04910685
A clinical trial for people with advanced systemic mastocytosis and other KIT-altered hematological malignancies
Trial Phase
Target Population
Aggressive SM, SM with associated hematologic neoplasm, mast cell leukemia and other KIT-altered hematological malignancies
Study Status
Active, recruiting
ClinicalTrials.gov
Study Number
NCT05609942
Learn more: clinicaltrials.gov/ct2/show/NCT05609942
Hormone-receptor-positive (HR+), HER2-negative (HER2-) breast cancer and other CDK2 vulnerable cancers
A clinical trial for people with cyclin E aberrant cancers and estrogen receptor-positive, HER2-negative breast cancer
Trial Phase
Target Population
Cyclin E aberrant ovarian cancer, endometrial cancer, gastric cancer and other solid tumors, and ER+, HER2- breast cancer
Study Status
Active, recruiting
ClinicalTrials.gov
Study Number
NCT05252416
Learn more: clinicaltrials.gov/ct2/show/NCT05252416
Pediatric cancers
A clinical trial for children and adolescents with solid tumors dependent on KIT or PDGFRA signaling
Trial Phase
Target Population
Solid tumors with a KIT or PDGFRA mutation and gliomas with an H3K27M mutation in pediatric patients
Study Status
Active, recruiting
ClinicalTrials.gov
Study Number
NCT04773782
Learn more: https://clinicaltrials.gov/ct2/show/NCT04773782
To learn more about our clinical trials, visit blueprintclinicaltrials.com or contact us in the U.S. at medinfo@blueprintmedicines.com or 1-888-BLU-PRNT (1-888-258-7768), and in Europe at medinfoeurope@blueprintmedicines.com or +31 85 064 4001.