Getting medicines to those who need them most
We recognize that the patients and families affected by life-threatening diseases anxiously await more effective medicines with each passing day. Knowing this drives us to work harder to deliver transformative treatments more swiftly.
We also seek to ensure any medicine we develop is safe and effective and follows the rigorous guidelines established by regulatory agencies.
We strive to balance these two complementary and vital goals in all that we do.
Our clinical trials
Systemic mastocytosis (SM)
Trial Phase
Target Population
Aggressive SM, SM with associated hematologic neoplasm and mast cell leukemia
Study Status
Active, fully enrolled
ClinicalTrials.gov
Study Number
NCT03580655
Trial Phase
Target Population
Indolent SM
Study Status
Active, fully enrolled
ClinicalTrials.gov
Study Number
NCT03731260
Trial Phase
Target Population
Indolent SM
Study Status
Active, recruiting
ClinicalTrials.gov
Study Number
NCT04910685
Learn more: clinicaltrials.gov/ct2/show/NCT04910685
Trial Phase
Target Population
Aggressive SM, SM with associated hematologic neoplasm, mast cell leukemia and other KIT-altered hematological malignancies
Study Status
Not yet recruiting
ClinicalTrials.gov
Study Number
NCT05609942
Learn more: https://clinicaltrials.gov/ct2/show/NCT05609942
RET-altered cancers
Trial Phase
Target Population
RET-altered non-small cell lung cancer (NSCLC), thyroid cancer (TC) or other solid tumors with a RET fusion or mutation
Study Status
Active, fully enrolled
ClinicalTrials.gov
Study Number
NCT03037385
Trial Phase
Target Population
First-line RET fusion-positive, metastatic NSCLC
Study Status
Active, recruiting
ClinicalTrials.gov
Study Number
NCT04222972
EGFR-mutated non-small cell lung cancer (NSCLC)
Trial Phase
Target Population
Treatment-resistant EGFR-mutated NSCLC
Study Status
Active, recruiting
ClinicalTrials.gov
Study Number
NCT04862780
Learn more: https://clinicaltrials.gov/ct2/show/NCT04862780
Trial Phase
Target Population
NSCLC and other cancers with EGFR exon 20 insertion mutations
Study Status
Active, recruiting
ClinicalTrials.gov
Study Number
NCT05241873
Learn more: https://clinicaltrials.gov/ct2/show/NCT05241873
CDK2-vulnerable cancers and estrogen receptor-positive (ER+), HER2-negative (HER2-) breast cancer
Trial Phase
Target Population
Cyclin E aberrant ovarian cancer, endometrial cancer, gastric cancer and other solid tumors, and ER+, HER2- breast cancer
Study Status
Active, recruiting
ClinicalTrials.gov
Study Number
NCT05252416
Learn more: https://clinicaltrials.gov/ct2/show/NCT05252416
Pediatric cancers
Trial Phase
Target Population
Solid tumors with a KIT or PDGFRA mutation and gliomas with an H3K27M mutation in pediatric patients
Study Status
Active, recruiting
ClinicalTrials.gov
Study Number
NCT04773782
Learn more: https://clinicaltrials.gov/ct2/show/NCT04773782
To learn more about our clinical trials, visit blueprintclinicaltrials.com or contact us in the U.S. at medinfo@blueprintmedicines.com or 1-888-BLU-PRNT (1-888-258-7768), and in Europe at medinfoeurope@blueprintmedicines.com or +31 85 064 4001.