Getting medicines to those who need them most
We recognize that the patients and families who battle life-threatening diseases anxiously await more effective medicines with each passing day. Knowing this drives us to work harder, to deliver transformative treatments more swiftly.
We also seek to ensure any medicine we develop is safe and effective and follows the rigorous guidelines established by regulatory agencies.
We strive to balance these two complementary and vital goals in all that we do.
To learn more about our clinical trials, visit blueprintclinicaltrials.com or contact our study director at studydirector@blueprintmedicines.com or (617) 714-6707.Our clinical trials
Gastrointestinal stromal tumors (GIST)
A clinical trial for people with advanced GIST
Trial Phase
Target Population
Advanced GIST
Study Status
Active, fully enrolled
ClinicalTrials.gov
Study Number
NCT02508532
Learn more: clinicaltrials.gov/ct2/show/NCT02508532
A clinical trial for people with advanced GIST
Trial Phase
Target Population
Third-line or fourth-line GIST
Study Status
Active, fully enrolled
ClinicalTrials.gov
Study Number
NCT03465722
Systemic mastocytosis (SM)
A clinical trial for people with advanced systemic mastocytosis
Trial Phase
Target Population
Aggressive SM, SM with an associated hematologic neoplasm, and mast cell leukemia
Study Status
Active, fully enrolled
ClinicalTrials.gov
Study Number
NCT02561988
Learn more: clinicaltrials.gov/ct2/show/NCT02561988
A clinical trial for people with advanced systemic mastocytosis
Trial Phase
Target Population
Aggressive SM, SM with an associated hematologic neoplasm, and mast cell leukemia
Study Status
Active, recruiting
ClinicalTrials.gov
Study Number
NCT03580655
A clinical trial for people with indolent or smoldering systemic mastocytosis
Trial Phase
Target Population
Indolent SM and smoldering SM
Study Status
Active, recruiting
ClinicalTrials.gov
Study Number
NCT03731260
RET-altered cancers
A clinical trial for people with RET-altered cancers
Trial Phase
Target Population
RET-altered non-small cell lung cancer (NSCLC), medullary thyroid cancer (MTC) or other solid tumors with a RET fusion or mutation
Study Status
Active, recruiting
ClinicalTrials.gov
Study Number
NCT03037385
Hepatocellular carcinoma (HCC)
Trial Phase
Target Population
FGFR4-activated HCC, defined as overexpression of FGF19 assessed by an immunohistochemistry test
Study Status
Active, recruiting
ClinicalTrials.gov
Study Number
NCT02508467
Learn more: clinicaltrials.gov/ct2/show/NCT02508467
Trial Phase
Target Population
Locally advanced or metastatic HCC; conducted in China
Study Status
Active, recruiting
ClinicalTrials.gov
Study Number
NCT04194801
Learn more: clinicaltrials.gov/ct2/show/NCT04194801