Clinical update

Blueprint Medicines Announces ASCO20 Data Presentations Highlighting Deep, Durable Clinical Activity and Well-Tolerated Safety Profile of Pralsetinib Across Broad Range of RET Fusion-Positive Tumors

A blueprint for a healthier tomorrow

We design and develop precision therapies, with the goal of transforming patient care. These include multiple programs for genomically defined cancers, rare diseases and cancer immunotherapy.

Our pipeline

Photo: L.O., living with non-small cell lung cancer

Clinical update

Blueprint Medicines Announces ASCO20 Data Presentations Highlighting Deep, Durable Clinical Activity and Well-Tolerated Safety Profile of Pralsetinib Across Broad Range of RET Fusion-Positive Tumors

A blueprint for a healthier tomorrow

We design and develop precision therapies, with the goal of transforming patient care. These include multiple programs for genomically defined cancers, rare diseases and cancer immunotherapy.

Our pipeline

Photo: L.O., living with non-small cell lung cancer

Precision that moves

Our uniquely targeted, scalable approach empowers the rapid design and development of new precision therapies and as we aim to stay one step ahead of disease.

Our platform

A promise to change the paradigm

We strive to improve human health with transformational medicines rooted in our leading expertise in protein kinases, which are proven drivers of disease.

Our company

Photo: R.T., living with gastrointestinal stromal tumor

Diversity sparks imagination

Our diverse team is passionate about science and thrives on working together to achieve the impossible. We use every opportunity to think differently, make bold decisions and pioneer novel solutions.

Our opportunities

Our 2020 Blueprint

2 marketed products
4 pending
marketing
applications
6 clinical-stage
therapeutic
candidates
8 research
programs

Our “2020 Blueprint” strategy establishes a planned path to transform Blueprint Medicines, by the end of 2020, into a global commercial enterprise focused on delivering a portfolio of precision therapies to patients with cancer and rare diseases. See our press release.

Our commitment to patients

At Blueprint Medicines, we work together in pursuit of one common goal: to dramatically improve the lives of people with genomically defined diseases.

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Photo: R.S., living with systemic mastocytosis

Clinical programs

Kinome illustration reproduced courtesy of Cell Signaling Technology, Inc.

Avapritinib

Development programs

  • Advanced gastrointestinal stromal tumors
  • Advanced systemic mastocytosis
  • Indolent and smoldering systemic mastocytosis
Learn more

Kinome illustration reproduced courtesy of Cell Signaling Technology, Inc.

Kinome illustration reproduced courtesy of Cell Signaling Technology, Inc.

PRALSETINIB

Development programs

  • Advanced RET-fusion non-small cell lung cancer
  • Advanced medullary thyroid cancer
  • Other RET-altered solid tumors
Learn more

Kinome illustration reproduced courtesy of Cell Signaling Technology, Inc.

Kinome illustration reproduced courtesy of Cell Signaling Technology, Inc.

FISOGATINIB

Development programs

  • Advanced hepatocellular carcinoma
Learn more

Kinome illustration reproduced courtesy of Cell Signaling Technology, Inc.

Kinome illustration reproduced courtesy of Cell Signaling Technology, Inc.

BLU-782

Development programs

  • Fibrodysplasia ossificans progressiva
Learn more

BLU-782 is an investigational ALK2 inhibitor being developed for the treatment of FOP. In October 2019, we entered into an exclusive, worldwide license agreement with Clementia Pharmaceuticals, a subsidiary of Ipsen, to develop and commercialize BLU-782.

Kinome illustration reproduced courtesy of Cell Signaling Technology, Inc.

Meet the Blue Crew

Meet the Blue Crew

Andrew Kim, International Head of Precision Medicine

As Blueprint Medicines’ first International Head of Precision Medicine, my role is to strategically plan and lead outreach to clinical investigators, healthcare providers and laboratories outside the United States to support the company’s portfolio of clinical-stage programs.

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The Lens

We aspire to pioneer multiple new scientific advances in disease biology and the design of precision therapies. To learn more about our scientific leadership and perspectives, visit The Lens.

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Unleashing the vast potential of kinase therapies

Our presentation at AAAAI

Seeking to deliver transformative medicines

Download Our latest corporate presentation
“We ignore traditional boundaries and let science drive us. It’s the only way to revolutionize how we treat cancer.”
Jeff Albers,
Chief Executive Officer
“We ignore traditional boundaries and let science drive us. It’s the only way to revolutionize how we treat cancer.”
Jeff Albers, Chief Executive Officer

Dare to be different

A strong team embraces different perspectives, opinions and ideas. We believe each level of our company should reflect our team’s diversity—and its excellence.

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