Aberrant driver: a molecular abnormality that underlies the growth and survival of a cancer (source) 

Cancer genomics revolution: encompasses initiatives including The Cancer Genomics Atlas (TGCA), the Cancer Genome Project (CGP), the International Cancer Genomics Consortium (ICGC) and other public and private tumor sequencing efforts. With these efforts, genomic analysis tools are enabling the identification of new therapeutic strategies to combat cancer from a genetic and mechanistic perspective.

Cancer genomics: cancer genomics is the study of the human cancer genome. Genomically driven: genomically-driven patient care is often referred to as personalized medicine. Personalized medicine is an emerging practice of medicine that uses an individual’s genetic profile to guide decisions made in regard to the prevention, diagnosis, and treatment of disease. Knowledge of a patient’s genetic profile can help doctors select the proper medication or therapy and administer it using the proper dose or regimen. (source)

Genomically driven: genomically driven patient care is often referred to as personalized medicine. Personalized medicine is an emerging practice of medicine that uses an individual’s genetic profile to guide decisions made in regard to the prevention, diagnosis, and treatment of disease. Knowledge of a patient’s genetic profile can help doctors select the proper medication or therapy and administer it using the proper dose or regimen. (source, source) 

Molecular diagnostics: molecular diagnostics categorizes cancer using technology such as mass spectrometry and gene chips and determines how the genes and proteins are interacting in a cell. It focuses upon patterns – gene and protein activity patterns – in different types of cancerous or precancerous cells. Molecular diagnostics uncovers these sets of changes and captures this information as expression patterns. Also called “molecular signatures,” these expression patterns are improving the clinicians’ ability to diagnose cancer. (source)

Pathology: the study of the essential nature of diseases and especially of the structural and functional changes produced by them. (source)

Resistance mechanisms: the fundamental processes involved in the failure of a drug to treat cancer cells. (source)